Psychosword,
Working with titanium is a whole nother ballgame. The titanium would have to be in a soft a state as possible and when the slide was finished it would have to be heat treated. Anyway, I am no engineer but it would be much more complicated than to just mill the slide out of titanium. I also think you are right in that a titanium slide would not have the necessary mass. A titanium frame on the other hand could be cast and probably must be cast because to mill a frame from titanium would be a long slow process.
I am no engineer. Who knows a thing or two about titanium
Come to think of it, if not a titanium frame how about a Scandium frame.
Tom, about the Colt lightweight Commanders holding up for thousands of rounds, I believe you but I have examined the R9 frame and it is scary thin is some places that I would feel better about if they were thicker.
Mike