Captain:
Ever since I started carrying a weapon in civilian life, I have assumed that I would probably not have to shoot more than once or twice in a self-defense situation -- if, God forbid, I have to shoot at all. With that in mind, I have settled on a prefragmented round as the leader with jacketed hollow points following along -- the thought being that, if the prefrag alone isn't enough, a followup JHP ought to complete the job.
I became a believer in "prefrags," regardless of caliber, after some experimentation at the range.
Regarding feeding, with that plastic tip, the Glasers feed as smoothly as "a hot knife through warm butter" -- both Blue and Silver.