Hi Fire:
Glasser was the first frangible ammo to actually work for defensive purposes. The original Glasser was shot pellets encased in a truncated cone jacket suspended in liquid Teflon. The round was then changed to promote greater tactical penetration. The idea was to punch through bone and then create a massive, but fairly shallow, wound channel to promote bleeding.
Magsafe was designed to have greater penetration than Glasser with multiple wound channels instead of the Glasser shot cloud. Magsafe uses various shot sizes suspended in an epoxy matrix.
RBCD was originally designed to be AP. This bullet was designed specifically for anti-terroist military and police action. The original bullet was lead free metal power held in place with a 3M plastic encased in a jacket on top of a plastic pellet. Since the powered metal was harder than steel, it would punch through dimond plate like butter, expanding like an umbrella in a fluid rich enviornment (ie. a body).
The non-military version uses lead power, but is otherwise the same construction. By using lead, it was classified as non-AP and approved for civilian sales by the BATF.
Since 1990, I've used frangible ammo in all of my pocket guns. I do so as a force multiplier. My intent for the defensive use of a firearm is to stop an attacker. It makes no difference to me if he lives or dies, just so he is not a threat to me or to my loved ones.
The key to stopping power is bullet placement. The benefit of frangible ammo is when bullet placement is less than ideal. These bullets create such massive injuries, that they cannot go unnoticed by a BG.
My primary defensive handgun is a Glock 36. I have never used frangible ammo in that gun. In fact I have never considered frangible ammo in any caliber larger than 38 Special. But when dealing with bullets smaller than .357, I view frangible ammo as a plus.
Right now, I still use standard pressure Magsafe Defender rounds in all of my pocketguns. But I will switch over to RBCD in my 32 ACP, and maybe my 380. As to my Rohrbaugh, I think I will stay with Magsafe.