Just found this string. Ah; .45ACP, my favorite round.
There is a lot of ground to cover but here goes:
1. 1911 - gold standard but not a good choice for personal defense as lawyers interpret "cock and lock" as intent when used for self defense.
2. Sig - I love the double action P220, in any configuration, and modest cost is a consideration.
3. Glock 36 - one of my personal favorites. Accurate, ugly and you never have to worry about customizing decisions (like 1911)
4. USFA 1911 - Magnificent piece but not cheap and more condusive to saving it as a "safe queen" than a daily carry
5. R45 - Doesn't exist and factory's failure to bring this to the market, (in a timely manner), despite huge market interest, is extremely disappointing in my view