I recently completed a 72-hour pistol training program, eight hours of which were devoted to shooting, reloading, and clearing malfunctions with either the strong hand only or weak hand only, assuming the other was injured and disabled. The reloading and malfunction clearing are not easy to practice on a normal shooting range, as the muzzle of the gun ends up pointing a lot of places other than downrange.
Prior to this training, I had done some left-hand shooting but it took this training to really do it well.
My preferred location for my BUG is in my left front pocket for the exact reason you brought up in the other thread.